Six key messages Microsoft is sending to Windows 8 developers

Oct 30, 2012 3:30 PM
Steve Ballmer looked relaxed on stage. Dressed down in a short sleeve shirt and pants, he smiled, he cracked jokes, and he energetically rallied the 2000-strong crowd of developers at the opening keynote to Microsoft’s Build conference on the company’s leafy Redmond, Washington campus.
It was a very different Ballmer on stage than we saw at other events in the past year, including last week’s stiff and formal Windows 8 launch event in New York City. The energetic tenor of Ballmer’s keynote and the second, Windows Phone 8-focused keynote, reflected the conference’s underlying theme of building out the Windows app ecosystem.
“In case it’s not clear, we’re all in with Windows 8,” Ballmer enthused during Tuesday’s Build opener. “Every group in Microsoft has contributed something that’s optimized for Windows 8 and Windows Phone 8 and touch.”
Tuesday’s keynote was clearly aimed at its audience of attending developers. But six trends and takeaways emerged from the talk that paint a clear picture of Microsoft’s view of the world.

Windows 8 has huge potential for apps

Ballmer opened things up Tuesday by noting that Microsoft has sold 4 million Windows 8 upgrades since the operating system went on sale three days ago. (For context, 670 million Windows 7 PCs have the potential to run Windows 8.) And current estimates are that some 400 million new devices will soon be shipping that developers can target.
“Our industry is rebuilding itself around new devices and services,” Ballmer noted before he called on developers to rise to the occasion. This new universe represents an opportunity for app developers to make one app for all PC forms. “It’s an unprecedented market. Hundreds of millions of users are dying to buy your application.”
Throughout the morning, Ballmer energetically rallied the troops. “This is a market in which you can do your best work, most innovative work, most creative work. Whatever you do as a developer, Windows 8 is the best opp for software developers today.
“I guarantee you this will be the best opportunity software developers will see.”

The apps are coming

At last week’s Windows 8 launch event, I was disappointed to hear so little about Windows 8 apps. During Tuesday’s keynote, Microsoft showed off more app icons on-screen, though it was unclear from how they were presented which ones were shipping now and which were coming soon.
The big news was that Ballmer announced that SAP, Dropbox, and Twitter have all announced plans for Windows 8 apps. This is exactly the kind of app development commitment consumers need to hear about and see more of in the coming weeks if people are to get excited about the modern interface in Windows. It’s a pity we didn’t hear this last week—a time when consumers were paying attention.
I still wish that that Microsoft could be more specific about the number of apps, and which apps are coming. To say that Windows 8 has more apps than other platforms’ app stores did at launch isn’t enough: The market has changed since those other App Stores debuted. And consumers want to know more what they’re buying into up front if they’re to have confidence in what Microsoft’s building.

Opportunities for new and more personal apps are huge

“Your application will be the most personal [it can be] if you choose to marry the opportunities in the system [with the software],” Ballmer told Build attendees. He emphasized the easy sharing between phone and PC, the ubiquity of various Windows experiences like search and share, and the strength of integrating with a Microsoft account and leveraging SkyDrive cloud storage.
“Search, share, live tiles, live activity—these are all things you can also do with your apps,” Ballmer said.
Perhaps Steven Guggenheimer, Microsoft’s corporate vice president of developer and platform evangelism, put it best: “The thing about the hardware ecosystem is that it doesn’t come to life without the software. It’s about the marriage of hardware and software—and services, in some cases.”
The reality check here is that what Guggenheimer espouses isn’t new. In fact, it’s what we’ve known for years now, and have seen epitomized by Apple’s iPhone hardware and its integration with the iOS app ecosystem.
The difference now is that we’re hearing this from stodgy old Microsoft—the company that arguably has the most vibrant and daringly different touch interface of any operating system today. It’s refreshing to hear, because it’s an admission that means Microsoft does indeed get what it needs to do to succeed in this brave new mobile world.

Businesses are interested in Windows 8

Before Tuesday, the signs around how enterprise’s interest in Windows were tepid at best. And that’s not surprising, given IT departments’ traditional reticence to jump on a major Windows upgrade.
But Ballmer announced Tuesday that Microsoft had sold some 10 million units of Windows 8 into the enterprise market. While no mention was made of when those unit might be deployed into the field, it still highlights burgeoning interest in the new operating system within the business world.
Even better: In talking with developers here at the event, it sounds like businesses are investigating how to make the jump to the new platform. One developer, Anthony Handley of Magenic, noted, “We have a lot of enterprise clients that are interested in taking their internal line-of-business applications to Windows 8.” 

Windows app development tools are robust, but not perfect

Before this event, I heard praise for Microsoft’s development environment. By comparison to what mobile tablet and phone developers are used to with Google’s Android, in particular, I’ve heard some waxing poetic in casual conversation about working with Microsoft’s tools. I’ve also heard grousing that Microsoft didn’t do enough to unify development for Windows 8 and Windows Phone 8, but on the whole, the vibe has been more positive than what I hear about Android.
Magenic’s Handley is a cross-platform developer for iOS, Android, and Windows. “Obviously there’s a good story around iOS,” he said. “But as a designer working with Microsoft tools, they’ve come a long way in the past couple of years. Designers can work in Blend, and developers can work in Visual Studio, and the two can be melded in the end. Underneath the covers, we’re working on the same code. So there’s a lot of things to be excited about.”
We saw a glimpse of why the tools matter in action during the Windows Phone 8 portion of the keynote. Tony Garcia of Unity showed off the first demo of the Unity platform on Windows Phone 8. He emphasized during his demo how the Shadowgun sample being shown off was really easy to develop and debug on the PC. And the visuals looked great. 

Also during the Windows Phone 8 keynote, we got a picture of Microsoft as a company that was being responsive to its developers’ needs to create compelling app experiences. Microsoft said it has delivered 90 percent of the top developer requests. That doesn’t say how many requests the company received, mind you, but it does show Microsoft is listening and responding.
Among the additions highlighted here: NFC support, SD card access, voice commands and navigation, in-app purchasing, peer-to peer networking, advanced networking, Bluetooth data transfers,text-to-speech, better multitasking, support for VOIP and video chat, and new proximity requests. Microsoft has also added deeper integration with native phone experiences; for example,it opened up access to its camera.

Microsoft is backing its developers

Every developer attending Build will walk away from this year’s conference with a 32GB Microsoft Surface RT tablet, 100GB of SkyDrive storage, and a Nokia Lumia 920 phone. The idea, of course, is to stimulate excitement and energy among developers for creating new apps for Windows 8 and Windows Phone 8.
Giving out new hardware to developers is common at developer-centric events like this: Google and RIM have done the same thing at their events. But this is a notable shift for Microsoft, and Ballmer’s plea after announcing the Surface giveaway to “please go out and build lots of apps” underscores that the company recognizes it needs to generate enthusiasm in its developer community around making apps.
Contrast that with the mood at last year’s Build conference in Anaheim. That’s when Ballmer and Steven Sinofsky held their big Windows 8 unveiling, and developers were gaping open-mouthed at the implications of the vast software changes.
This year, Microsoft shifted its attention from simply introducing Windows 8 to focusing on getting developers to create apps for its new platforms across desktop, laptop, tablet, and phone. And this time, we had real, shipping hardware to spark app developers’ creativity.
“I think the creativity of your app is not just a function of what we build in [the software] but also of the hardware it sits on,” Ballmer told developers.
In the end, one of Ballmer’s lines particularly underscored that Microsoft’s success rides on more than what the company itself can control. “We need your support. Need your commitment [to building apps],” said Ballmer.
That right there sums up Microsoft’s Windows 8 “if you build it they will come” gamble. Windows 8 and Windows Phone 8 are here. Now all Microsoft—and us consumers—need is for developers to come and build out the ecosystem.


The Cure for Type II Diabetes using Nano Technology

“Nano Technology will make great leaps and bounds in the research of molecular chemistry and biology to be the next tranport system for the cure of diseases where the development of drugs of all kinds can be used to target specific cells and organs, even a greater understanding of the composite of matter, to create water into wine, by manipulating the structure of matter.” – Contributed by Oogle.

Warning : Please do not take your insulin injection when you are fasting or on a drip without food as the toxity can inflict damages especially with a low sugar count.

The Cure for Type II Diabetes

The problem
Most patients inject insulin at the abdomen area and by the time the insulin reaches the feet and the eyes, the dosage is too little for prevention, but if you increase the dosage even higher, there will be toxity in the abdomen area.
The Cure and Solution
Using Nano technology, it is possible to encapsulate a molecule of insulin via a transport system which will target the molecules and DNA of lets say the eyes, where the info and target will be compared until it reaches its destination to release the payload. As such, the future of medicine will be using this technology to treat any organs or areas in the body, where even the payload and the frequency can be controlled, a cure for all diseases.
– Contributed by Oogle.  


Molecular cloning is the laboratory process used to create recombinant DNA.[1][2][3][4] It is one of two widely-used methods (along with polymerase chain reaction, abbr. PCR) used to direct the replication of any specific DNA sequence chosen by the experimentalist. The fundamental difference between the two methods is that molecular cloning involves replication of the DNA within a living cell, while PCR replicates DNA in the test tube, free of living cells.
Formation of recombinant DNA requires a cloning vector, a DNA molecule that will replicate within a living cell. Vectors are generally derived from plasmids or viruses, and represent relatively small segments of DNA that contain necessary genetic signals for replication, as well as additional elements for convenience in inserting foreign DNA, identifying cells that contain recombinant DNA, and, where appropriate, expressing the foreign DNA. The choice of vector for molecular cloning depends on the choice of host organism, the size of the DNA to be cloned, and whether and how the foreign DNA is to be expressed.[5] The DNA segments can be combined by using a variety of methods, such as restriction enzyme/ligase cloning or Gibson assembly.
In standard cloning protocols, the cloning of any DNA fragment essentially involves seven steps: (1) Choice of host organism and cloning vector, (2) Preparation of vector DNA, (3) Preparation of DNA to be cloned, (4) Creation of recombinant DNA, (5) Introduction of recombinant DNA into the host organism, (6) Selection of organisms containing recombinant DNA, (7) Screening for clones with desired DNA inserts and biological properties.[4] These steps are described in some detail in a related article (molecular cloning).
Following transplantation into the host organism, the foreign DNA contained within the recombinant DNA construct may or may not be expressed. That is, the DNA may simply be replicated without expression, or it may be transcribed and translated so that a recombinant protein is produced. Generally speaking, expression of a foreign gene requires restructuring the gene to include sequences that are required for producing a mRNA molecule that can be used by the host’s translational apparatus (e.g. promoter, translational initiation signal, and transcriptional terminator).[6] Specific changes to the host organism may be made to improve expression of the ectopic gene. In addition, changes may be needed to the coding sequences as well, to optimize translation, make the protein soluble, direct the recombinant protein to the proper cellular or extracellular location, and stabilize the protein from degradation.[7

  • Recombinant human insulin. Recombinant insulin has almost completely replaced insulin obtained from animal sources (e.g. pigs and cattle) for the treatment of insulin-dependent diabetes. A variety of different recombinant insulin preparations are in widespread use.[11] Recombinant insulin is synthesized by inserting the human insulin gene into E. coli, which then produces insulin for human use.[12]

The best steps Japan could make is to settle the dispute with China quickly

Kenya Hirose and Shingo Sugime
The Yomiuri Shimbun/Asia News Network
Thursday, Nov 01, 2012

JAPAN – Before taking additional monetary-easing steps for a second month in a row, the Bank of Japan apparently struggled to decide what specific steps to take amid intense pressure from the market and the government.
The central bank’s nine-member Policy Board decided to take the additional easing measures Tuesday. It also issued a joint statement with the government expressing their shared view that the biggest challenge for the economy is overcoming deflation as soon as possible.
In his blog updated Tuesday, Prime Minister Yoshihiko Noda welcomed the bank’s move, saying, “This will be yet another great step for the economy toward overcoming deflation early.”
Finance Minister Koriki Jojima also hailed the action, saying to reporters, “Monetary-easing measures even bolder than the previous ones have been taken by the central bank.”
However, the latest easing was not necessarily in line with a plan envisaged earlier by the central bank.
When the bank decided to increase its fund mainly for asset purchases by 10 trillion yen in September, Bank of Japan Gov. Masaaki Shirakawa said the move was “taken in anticipation of downward revisions in the outlook of the overall economy and commodity prices.”
A prevailing view within the bank had been that it should try to ascertain the effect of September’s monetary easing. But the situation changed drastically Oct. 17, when Noda instructed economic ministers to map out emergency economic measures.
In the financial market, speculation grew quickly that the central bank, in line with the government, would take additional monetary-easing measures worth 20 trillion yen–even bolder than the previous easing.
On Oct. 22, the central bank released its report on local economies, which highlighted the adverse effect on the economy wrought by the soured relations with China over the government’s purchase of three of the Senkaku Islands in Okinawa Prefecture from their private owner.
Following the report, calls for additional easing measures increased, even with the central bank. Masayoshi Amamiya, head of the bank’s Osaka branch, said, “There’s a danger of the [deteriorated] Japan-China relationship adversely affecting the economy for a protracted period.”
Seiji Maehara, state minister for economic and fiscal policy in the newly reshuffled Cabinet, had urged the central bank to take further steps–even unconventional measures including purchasing foreign bonds–to ensure the economy could overcome deflation before the planned consumption tax increase in April 2014.
According to government sources, Noda was well aware of the problems Maehara was pointing to. The Finance Ministry, which Noda trusts highly, had been working behind the scenes to coordinate the views of the government and the central bank.
However, even though both sides were in agreement over taking concerted action, views were divided within the central bank as to what steps the bank should take.
Under pressure from the government to take further easing steps, and taking into consideration the view of the major opposition Liberal Democratic Party–led by Shinzo Abe, who has been calling on the bank to take powerful easing steps–a senior bank official said the bank should increase the fund by more than 20 trillion yen in one shot.
At the same time, there were strong calls to limit the injection to 10 trillion yen to avoid excessive “dependency on the central bank” in overcoming deflation and putting the economy back on a sustainable growth path.
Facing increased pressure to act, and knowing that if the market deemed the measures inefficient the bank could be seen as taking a backward stance, the BOJ made its decision at the 11th hour with only a handful of options.
The bank concluded that its best possible choice was to increase its asset-purchase fund by 11 trillion yen, bringing it to a total of about 91 trillion yen, and to establish a loan-stimulating facility to boost lending by commercial banks.
The bank reportedly calculated that combining two measures alone, the monetary easing would be worth more than 20 trillion yen–a level the market had hoped for.
Effects of the central bank’s easing decision were still yet to be seen Tuesday, as the yen edged upward and the stock market fell overall.
At a gathering in central Tokyo on Tuesday evening, Abe strongly criticised the bank’s latest move.
“The yen moved upward instead,” Abe said. “Piecemeal easing like this is of no use.”
Have you calculated the economic costs with the dispute with China? Your economy depends greatly on exports to China and the ability to setup factories in China for low production costs, I do not think you have factored in everything? It even cost more than the entire islands you are after so I think it is a stupid move, my advice is to settle the dispute quickly and put everything behind, there is greater money to be made now things are starting to pick up, it will help you save more than half your budget if you can resolve things amicably.
– Contributed by Oogle.